Case Study on "Understanding Gram-Negative Folliculitis: Causes, Symptoms, and Treatment Approaches

  • A.H.V Santhoshi Associate Professor, Department of Pharmaceutical Chemistry, Avanthi Institute of Pharmaceutical Sciences
  • Vana Swathi Priya Avanthi Institute of Pharmaceutical Sciences

Abstract

Gram-negative folliculitis is a dermatological condition characterized by the presence of gram-negative bacteria, notably Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens, Klebsiella, and Proteus species. This abstract encapsulates key findings from a comprehensive case study conducted to unravel the intricacies of gram-negative folliculitis. Through detailed case profiles, we explore diverse manifestations, such as those arising from prolonged antibiotic use, spa pool exposure to Pseudomonas aeruginosa, and freshwater related Aeromonas hydrophilia infections. The study delves into the unique staining pattern of gram-negative bacteria, emphasizing the significance of the Gram stain in diagnosis. Implications for accurate diagnosis and tailored treatment strategies, including the use of antibiotics effective against gram-negative bacteria, are discussed. The case a 24-year-old female comes to the hospital seeking treatment for acne-related problems and has been using Self-medication. This case study contributes valuable insights to the evolving landscape of dermatological conditions associated with gram-negative bacteria, facilitating a more nuanced understanding for medical practitioners, and paving the way for enhanced patient care. Gram-negative folliculitis in acne and rosacea patients is best treated with isotretinoin (0.5-1 mg/kg daily for 4-5 months).

Keywords: Gram-negative folliculitis, Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens, Klebsiella, Proteus species, Dermatological condition.

References

1. Durdu M, Ilkit M. First step in the differential diagnosis of folliculitis: cytology. Crit Rev Microbiol. 2013;39(1):9–25. doi:10.3109/1040841X.2012.682051. PubMed
2. Böni R, Nehrhoff B. Treatment of gram-negative folliculitis in patients with acne. Am J Clin Dermatol. 2003;4(4):273-6. doi: 10.2165/00128071-200304040-00005. PMID: 12680804.
3. Poli F, Prost C, Revuz J. Folliculites à bacilles gram négatif [Gram-negative bacteria folliculitis]. Ann Dermatol Venereol. 1988;115(8):797-800. French. PMID: 2974267.
4. Amichai B, Grunwald MH, Halevy S. [Treatment of gram-negative folliculitis with isotretinoin]. Harefuah. 1993 Feb 15;124(4):200-1, 247. Hebrew. PMID: 8495899.
5. https://escholarship.org/uc/item/9np1012t.
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How to Cite
A, H. S., & Vana, S. P. (2019). Case Study on "Understanding Gram-Negative Folliculitis: Causes, Symptoms, and Treatment Approaches. Journal of Integral Sciences, 2(3), 6-8. Retrieved from https://www.jisciences.com/index.php/journal/article/view/74
Section
Case Studies & Reports