"Prednisolone's Therapeutic Role and Challenges in Managing Steroid-Dependent Nephrotic Syndrome"
Abstract
This case study investigates the therapeutic application of prednisolone in the management of steroid-dependent nephrotic syndrome (SDNS) and the complications that come with it. Steroid-dependent nephrotic syndrome is a clinical quandary in which individuals relapse after reducing or discontinuing corticosteroid medication. In these circumstances, prednisolone, a routinely administered corticosteroid, plays a critical role in establishing and maintaining remission. The study looks on the effects of prednisolone on proteinuria, inflammation, and edema in patients with SDNS.
Keywords:
steroid-dependent nephrotic syndrome, corticosteroid, inflammation, edema.
References
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7. Larkins NG, Liu ID, Willis NS, et al. Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children. Cochrane Database Syst Rev, 2020.
2. Samuel S, Bitzan M, Zappitelli M, et al. Canadian Society of Nephrology Commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis: management of nephrotic syndrome in children. Am K Kidney Dis. 2014;63:354–362.
3. Kdigo Clinical Practice Guidelines for Glomerulonephritis. 2012, vol. 2, issue 2, pp 163-171.
4. Mihaela Balgradean. Current pathology in pediatric nephrology. Revised and added second edition, 2016
5. Vivarelli M, Massella L, Ruggierro B, Emma F. Minimal change disease. Clin J Am Soc Neprol. 2017;12:332–345.
6. Schijvens AM, Teeninga N, Dorresteijn EM, et al. Steroid treatment for the first episode of childhood nephrotic syndrome: comparison of the 8 and 12 week regimen using an individual patient data meta-analysis. Eur J Pediatr. 2021;180:2849–2859.
7. Larkins NG, Liu ID, Willis NS, et al. Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children. Cochrane Database Syst Rev, 2020.
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How to Cite
Y, V., B, S., & Bammidi, J. S. (2019). "Prednisolone’s Therapeutic Role and Challenges in Managing Steroid-Dependent Nephrotic Syndrome". Journal of Integral Sciences, 2(4), 5-8. Retrieved from https://www.jisciences.com/index.php/journal/article/view/75
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Case Studies & Reports
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